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Ultra-processed food consumption associates with higher cardiovascular risk in rheumatoid arthritis

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ARTICLE DOWNLOAD

Ultra-processed food consumption associates with higher cardiovascular risk in rheumatoid arthritis

10$

Fabiana Infante Smaira, Bruna Caruso Mazzolani, Tiago Peçanha, Kamila Meireles dos Santos, Diego Augusto Nunes Rezende, Maria Eugênia Araujo, Karina Bonfiglioli, Fernanda Baeza Scagliusi, Fabiana Braga Benatti, Ana Lúcia de Sá Pinto, Fernanda Rodrigues Lima, Rosa Maria R. Pereira, Hamilton Roschel, Bruno Gualano & Ana Jéssica Pinto 

Abstract

To investigate the association between food consumption stratified by processing level and cardiovascular risk factors in rheumatoid arthritis. In this cross-sectional study, 56 patients (age: 62.5 ± 7.9 years, BMI: 28.4 ± 5.1 kg/m2) had food consumption evaluated according to the processing level (e.g., unprocessed or minimally processed foods, processed foods, and ultra-processed foods) and associated with cardiovascular risk factors. The most prevalent food processing level was unprocessed or minimally processed foods (42.6 ± 12.6% of total energy intake [TEI]), followed by processed (24.2 ± 11.9%TEI), ultra-processed (18.1 ± 11.8%TEI), and culinary ingredients (15.1 ± 6.4%TEI). Adjusted regression models showed that higher consumption of ultra-processed foods was positively associated with Framingham risk score (β = 0.06, CI: 95% 0.001, 0.11, p = 0.045) and glycated hemoglobin (β = 0.04, CI: 95% 0.01, 0.08, p = 0.021). In contrast, higher consumption of unprocessed or minimally processed foods was associated with lower 10-year risk of developing cardiovascular diseases (β = −0.05, CI: 95% 0.09, −0.003, p = 0.021) and LDL (β = −1.09, CI: 95% 1.94, −0.24, p = 0.013). Patients with rheumatoid arthritis consuming more ultra-processed foods showed worse metabolic profile, whereas those consuming more unprocessed or minimally processed foods had lower cardiovascular risks. A food pattern characterized by a high ultra-processed food consumption appears to emerge as a novel, modifiable risk factor for cardiovascular diseases in rheumatoid arthritis.

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Year 2020
Language English
Format PDF
DOI 10.1007/s10067-019-04916-4