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Synthesis and Cytotoxic Activity of a Series of Functionalized Maleopimarimides

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ARTICLE DOWNLOAD

Synthesis and Cytotoxic Activity of a Series of Functionalized Maleopimarimides

10$

R. N. Malikova, I. M. Sakhautdinov, E. O. Terenteva, Z. S. Khashimova, M. S. Yunusov & Sh. S. Azimova 

New functionalized maleopimarimides were prepared. Their cytotoxicity against tumor cell lines (HeLa, HEp-2) was studied. Diterpenoids 6, 9, and 10 with allene fragments possessed the greatest cytotoxicity and could be considered lead compounds with potential antitumor activity.

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Year 2020
Language English
Format PDF
DOI 10.1007/s10600-020-02953-z