ARTICLE DOWNLOAD

Financial toxicity and its associated patient and cancer factors among women with breast cancer: a single-center analysis of low-middle income region in China

10$
ARTICLE DOWNLOAD

Financial toxicity and its associated patient and cancer factors among women with breast cancer: a single-center analysis of low-middle income region in China

10$

Jingfeng Jing, Ran Feng, Xiaojun Zhang, Ming Li & Jinnan Gao 

Abstract

Purpose

To assess the financial toxicity (FT) and to investigate patients and cancer characteristic that associated with it in patients admitted in a tertiary hospital in central China.

Methods

This was a cross-sectional study of 166 patients from 188 with stage 0-III women breast cancer admitted in Bethune hospital in Taiyuan, Shanxi province during January–May 2019. FT was self-reported using of financial Toxicity Comprehensive Rating Scale (COST-FACIT). Patients’ sociodemographic factors, clinical examination, and cancer treatment were collected from questionnaire and hospital record. The financial concern and coping strategy was self-reported. Factors associated with FT were identified using linear regression analysis.

Results

Of the 166 completed the survey, the COST score ranged 0–40 with a mean of 21.2 (median 22.5, standard deviation 8.1). On multivariate linear regression analysis, older age (β coefficient: 0.20, 95% CI 0.11–0.29, p < 0.001), higher household income (β coefficient: 3000–5000 Yuan: 7.88, 95% CI 4.74–11.01, p < 0.001; ≥ 5000 Yuan: 12.81, 95% CI 9.54–16.08, p < 0.001) were positively associated with COST scores. Advanced cancer stage was the strongest predictor of FT among the cancer characteristics (β coefficient: − 4.52, 95% CI − 7.13–1.92, p = 0.001). To cope with the FT, 131 (78.8%) patients decreased non-medical expenses, and 56 (33.7%) reduced or quitted treatment.

Conclusions

FT was significantly associated with patient’s age, income, and cancer stage. Women having financial concerns after diagnosis were more likely to reduce their non-medical expenses and even quit treatments. Clinicians should take into account the FT levels in all patients and work out appropriate treatment strategies for optimal clinical outcome.

Only units of this product remain
Year 2020
Language English
Format PDF
DOI 10.1007/s10549-020-05632-3